Our research is crucial for the development of effective treatments for endometrosis and for preventing early embryo mortality in mares.
We focus on understanding the molecular foundations of physiological and pathological processes occurring in the reproductive system of horses, especially the mechanisms of tissue fibrosis during endometriosis, with particular emphasis on the interactions between stromal connective tissue cells and immune cells, metabolism, and the role of cell death.
We also conduct studies on the physiology of early pregnancy in mares, analyzing immunological processes during placentation and embryo implantation.
Our research is conducted using a large animal model and based on tissue cultures and endometrial cell cultures: epithelial cells and fibroblasts.
We use molecular biology techniques, protein detection methods, omics studies (transcriptomics, proteomics, metabolomics), and imaging techniques at the cellular and tissue levels.
The results of our research contribute to the development of reproductive biotechnologies, which is our response to the needs of breeders and veterinarians specializing in equine reproduction.